| Ministeries | Ministers |
| Chief Minister, SC,ST,BC,Minorities Welfare, Municipal Administration & Urban Development, Energy,Coal,GAD and All other portfolios not alloted. | Sri Kalvakuntla Chandrashekar Rao |
| Deputy Chief Minister, Home, Prisons and Fire Services | Sri Md. Mohamood Ali |
| Forest & Environment and S&T, Endowments and Law | Sri A. Indrakaran Reddy |
| Animal Husbandry, Fisheries, Dairy Development Corp. and Cinematography | Sri Talasani Srinivas Yadav |
| Energy | Sri Guntakandla Jagadish Reddy |
| Medical & Health and Family Welfare | Sri Etela Rajendra |
| Agriculture, Co-operation, Marketing | Sri Singireddy Niranjan Reddy |
| Panchayat Raj & Rural Development and RWS Rural water supply. | Sri Errabelli Dayakar Rao |
| Scheduled Castes Development, Minority Welfare and Senior Citizen Welfare | Sri Koppula Eshwar |
| Excise & Prohibition, Sports and Youth Services, Archaeology | Sri V. Srinivas Goud |
| Roads & Buildings, Legislative Affairs and Housing | Sri Vemula Prashanth Reddy |
| Labour & Employment, Factories | Sri Chamakura Malla Reddy |
| Finance | Sri Thanneeru Harish Rao |
| MA&UD, Industries & IT E&C | Sri KT Rama Rao |
| Education | Smt. Patlolla Sabitha Indra Reddy |
| BC Welfare, Food & Civil Supplies & Consumer Affairs | Sri Gangula Kamalakar |
| ST Welfare, Women & Child Welfare | Smt. Satyavathi Rathod |
| Transport | Sri Puvvada Ajay Kumar |